Curtis A Nutter

Curtis A Nutter,

PostDoc Associate

Department: Molecular Genetics & Microbiology
Business Phone: (352) 273-8156
Business Email: curtis.nutter@gmail.com

Publications

2023
Autistic traits in myotonic dystrophy type 1 due to MBNL inhibition and RNA mis-splicing.
Research square. [DOI] 10.21203/rs.3.rs-3221704/v1. [PMID] 37645891.
2023
Choroid plexus mis-splicing and altered cerebrospinal fluid composition in myotonic dystrophy type 1.
Brain : a journal of neurology. 146(10):4217-4232 [DOI] 10.1093/brain/awad148. [PMID] 37143315.
2021
The sustained expression of Cas9 targeting toxic RNAs reverses disease phenotypes in mouse models of myotonic dystrophy type 1.
Nature biomedical engineering. 5(2):157-168 [DOI] 10.1038/s41551-020-00607-7. [PMID] 32929188.
2020
HNRNPA1-induced spliceopathy in a transgenic mouse model of myotonic dystrophy.
Proceedings of the National Academy of Sciences of the United States of America. 117(10):5472-5477 [DOI] 10.1073/pnas.1907297117. [PMID] 32086392.
2020
Loss of MBNL1 induces RNA misprocessing in the thymus and peripheral blood.
Nature communications. 11(1) [DOI] 10.1038/s41467-020-15962-x. [PMID] 32332745.
2019
A developmentally regulated spliced variant of PTBP1 is upregulated in type 1 diabetic hearts.
Biochemical and biophysical research communications. 509(2):384-389 [DOI] 10.1016/j.bbrc.2018.12.150. [PMID] 30594394.
2019
Cell-type-specific dysregulation of RNA alternative splicing in short tandem repeat mouse knockin models of myotonic dystrophy.
Genes & development. 33(23-24):1635-1640 [DOI] 10.1101/gad.328963.119. [PMID] 31624084.
2018
Intron retention induced by microsatellite expansions as a disease biomarker.
Proceedings of the National Academy of Sciences of the United States of America. 115(16):4234-4239 [DOI] 10.1073/pnas.1716617115. [PMID] 29610297.
2017
Developmentally regulated alternative splicing is perturbed in type 1 diabetic skeletal muscle.
Muscle & nerve. 56(4):744-749 [DOI] 10.1002/mus.25599. [PMID] 28164326.
2016
Dysregulation of RBFOX2 Is an Early Event in Cardiac Pathogenesis of Diabetes.
Cell reports. 15(10):2200-2213 [DOI] 10.1016/j.celrep.2016.05.002. [PMID] 27239029.
2016
Rbfox2 function in RNA metabolism is impaired in hypoplastic left heart syndrome patient hearts.
Scientific reports. 6 [DOI] 10.1038/srep30896. [PMID] 27485310.
2013
Reactivation of fetal splicing programs in diabetic hearts is mediated by protein kinase C signaling.
The Journal of biological chemistry. 288(49):35372-86 [DOI] 10.1074/jbc.M113.507426. [PMID] 24151077.

Grants

Oct 2023 ACTIVE
Escaping X chromosome inactivation to mitigate X-linked expansion and deletion diseases
Role: Principal Investigator
Funding: XTRAORDINARY JOY FOUNDATION
Sep 2023 ACTIVE
Mouse Dmpk CTG expansion knock in models for myotonic dystrophy (MDA 1070134)
Role: Principal Investigator
Funding: MUSCULAR DYSTROPHY ASSO
Jan 2018 – Dec 2019
Congenital myotonic dystrophy:pathomechanism and therapeutic development
Role: Principal Investigator
Funding: WYCK FOUNDATION

Contact Details

Phones:
Business:
(352) 273-8156
Emails:
Addresses:
Business Mailing:
PO BOX 103610
GAINESVILLE FL 326100001
Business Street:
2033 MOWRY RD
GAINESVILLE FL 32611