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Center for NeuroGenetics College of Medicine

Shu Guo,

AST SCTST

Department: Molecular Genetics & Microbiology

Business Phone: (352) 273-5188

Business Email: s.guo@ufl.edu

Publications

Academic Articles

CASP8 intronic expansion identified by poly-glycine-arginine pathology increases Alzheimer’s disease risk.
2025

Journal

Proceedings of the National Academy of Sciences of the United States of America.

Volume/Issue

122(7)

[DOI]

10.1073/pnas.2416885122.

[PMID]

39937857.

2 citations PubMed Publisher’s Site
RAN proteins in neurodegenerative disease: Repeating themes and unifying therapeutic strategies.
2022

Journal

Current opinion in neurobiology.

Volume/Issue

72:160-170

[DOI]

10.1016/j.conb.2021.11.001.

[PMID]

34953315.

15 citations PubMed Publisher’s Site
Survival and Motor Phenotypes in FVB C9-500 ALS/FTD BAC Transgenic Mice Reproduced by Multiple Labs.
2020

Journal

Neuron.

Volume/Issue

108(4):784-796.e3

[DOI]

10.1016/j.neuron.2020.09.009.

[PMID]

33022226.

34 citations PubMed Publisher’s Site
Metformin inhibits RAN translation through PKR pathway and mitigates disease in C9orf72 ALS/FTD mice.
2020

Journal

Proceedings of the National Academy of Sciences of the United States of America.

Volume/Issue

117(31):18591-18599

[DOI]

10.1073/pnas.2005748117.

[PMID]

32690681.

107 citations PubMed Publisher’s Site
Antibody Therapy Targeting RAN Proteins Rescues C9 ALS/FTD Phenotypes in C9orf72 Mouse Model.
2020

Journal

Neuron.

Volume/Issue

105(4):645-662.e11

[DOI]

10.1016/j.neuron.2019.11.007.

[PMID]

31831332.

76 citations PubMed Publisher’s Site

Contact Details

Phones:

Business:: (352) 273-5188

Emails:

Business:: s.guo@ufl.edu

Addresses:

Business Mailing:: PO Box 103610
GAINESVILLE FL 326103010
Business Street:: 2033 MOWRY RD
GAINESVILLE FL 32610