Alzheimer’s Disease (AD) is the most common cause of dementia in the elderly. It begins with subtle memory loss and progresses relentlessly. AD ultimately involves higher cognitive function capabilities, leading to complete incapacitation and death. It is a complex disease with many contributing factors (including genetics) which is one of the reasons there is currently no cure for this devastating disorder.
Many of the neurodegenerative disorders such as amyotrophic lateral sclerosis (ALS) that are studied at the Center for NeuroGenetics have molecular and phenotypic similarities with Alzheimer’s Disease (AD). Lessons learned on how complex diseases like ALS arise and how they can be treated may provide clues to other neurological diseases with similar disease mechanisms like AD. As scientists we are driven to understand the underlying biology that causes neurological disease and apply this knowledge to improving human health.
Our research on Alzheimer’s disease focuses on applying the fundamental knowledge gained from understanding the molecular mechanisms of other neurodegenerative repeat expansion diseases. How cellular processes react to stress, cope with aging, and handle injury are common scientific avenues of research that can be applied across a large group of diseases.
Get Involved with Research
If you would like information about any of the opportunities listed below, please contact Deborah Morrison.
We are currently recruiting for a variety of trials and studies. Click the link below to learn more about our work and to see if you’re eligible.
Patients with neurodegenerative diseases being treated at the Fixel Institute may participate in these ongoing studies. The goal is to collect biospecimens to study in the lab.
Are you a passionate student or post-doc looking making to an impact on Neurogenetic research at the University of Florida? Candidates are encouraged to contact individual CNG faculty members to inquire about research opportunities in the CNG.